Methods for assessing efficacy of chemotherapeutic agents
US8039213B2 · kind B2 · utility
1Cited by
34References
16Claims
0Family size
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Key dates
| Filing date | Oct 5, 2010 |
| Grant date | Oct 18, 2011 |
| Priority date | — |
| Expiry date | Oct 5, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/136
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods are provided for accurately predicting efficacy of chemotherapeutic agents. Methods of the invention increase the positive predictive value of chemosensitivity assays by assessing both the ability of a chemotherapeutic to destroy cells and the genetic propensity of those cells for resistance. Results obtained using methods of the invention provide insight into the in vivo effectiveness of a therapeutic, and lead to more effective chemotherapeutic treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.