Pyrazine-2-carboxamide derivatives to treat diseases mediated by blockade of the epithelial sodium channel
US8039472B2 · kind B2 · utility
6Cited by
4References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 10, 2008 |
| Grant date | Oct 18, 2011 |
| Priority date | — |
| Expiry date | Dec 10, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of Formula Iin free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.