Compounds and compositions as protein kinase inhibitors
US8039479B2 · kind B2 · utility
37Cited by
12References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 20, 2007 |
| Grant date | Oct 18, 2011 |
| Priority date | — |
| Expiry date | Jun 29, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.