Transdermal delivery system for polynucleotides
US8041421B2 · kind B2 · utility
20Cited by
12References
14Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 25, 2005 |
| Grant date | Oct 18, 2011 |
| Priority date | — |
| Expiry date | Dec 15, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A system for intradermal or transdermal delivery of oligonucleotides or polynucleotides and methods of use thereof employ an apparatus that generates micro-channels in the skin of a subject in conjunction with a pharmaceutical composition comprising an oligonucleotide or polynucleotide, wherein the oligonucleotide or polynucleotide can be delivered into the organism through the micro-channels. The system and methods achieve expression of target proteins encoded by the polynucleotides, and hence are useful in immunization and gene therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.