Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
US8041515B2 · kind B2 · utility
22Cited by
56References
35Claims
0Family size
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Key dates
| Filing date | Sep 20, 2007 |
| Grant date | Oct 18, 2011 |
| Priority date | — |
| Expiry date | Feb 9, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/502
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods of multi-dimensional profiling of biologically active agents and determining their effects on biological systems. The methods of the present invention include real-time impedance monitoring of cellular responses to biologically active agents and categorization of cellular kinetic profiles into mechanism specific cellular response profile groups. The grouping of similar cellular response profiles allows the correlation between agent and mechanism, thus allowing for the identification of potential therapeutic applications of agents or further study of cellular responses or mechanisms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.