Infection and treatment of neoplasms with vesicular stomatitis virus
US8043612B2 · kind B2 · utility
13Cited by
20References
58Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 18, 2008 |
| Grant date | Oct 25, 2011 |
| Priority date | — |
| Expiry date | Jun 4, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18151
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.