Patent · US Active

Shell-and-core dosage form approaching zero-order drug release

US8043630B2 · kind B2 · utility

26Cited by

33References

20Claims

0Family size

Assignee

Depomed, Inc. · US

Inventors

Bret Berner
Jenny Louie-Helm · Fremont, US
Gloria M. Gusler · Cupertino, US
John N. Shell · Rocklin, US

Key dates

Filing date	Apr 29, 2010
Grant date	Oct 25, 2011
Priority date	—
Expiry date	Apr 29, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gastric retention of the dosage form by swelling upon imbibition of gastric fluid to size that is retained in the stomach during the postprandial or fed mode.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.