6-cyclylmethyl- and 6-alkylmethyl pyrazolo[3,4-D]pyrimidines, methods for their preparation and methods for their use to treat impairments of perception, concentration learning and/or memory

US8044060B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Martin Hendrix · Tarrytown, US
• Lars Bärfacker · Oberhausen, DE
• Christina Erb · Wiesbaden, DE
• Frank-Thorsten Hafner · Wuppertal, DE
• Heike Heckroth · Wuppertal, DE
• Dagmar Karthaus · Solingen, DE
• Adrian Tersteegen · Wuppertal, DE
• Franz-Josef van der Staay · Dronten, NL
• Marja Van Kampen · Neu-Isenburg, DE

Key dates

• Filing date: Apr 28, 2004
• Grant date: Oct 25, 2011
• Expiry date: Jan 5, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described are 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolo[3,4-d]pyrimidines of the formula (I):as defined herein, processes for their preparation and their use for producing medicaments for treating impairment of perception, concentration, learning and/or memory.