Synthetic bifunctional molecules containing drug moiety and pharmacokinetic modulating moiety
US8044099B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Dec 13, 2004 |
| Grant date | Oct 25, 2011 |
| Priority date | — |
| Expiry date | Oct 2, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bifunctional molecules and methods for their use are provided. The subject bifunctional molecules are conjugates of a drug moiety and a pharmacokinetic modulating moiety, where these two moieties are optionally joined by a linking group. The bifunctional molecules are further characterized in that they exhibit at least one modulated pharmacokinetic property upon administration to a host as compared to a free drug control. The subject bifunctional molecules find use in a variety of therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.