Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
US8044103B2 · kind B2 · utility
5Cited by
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21Claims
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Key dates
| Filing date | Feb 22, 2007 |
| Grant date | Oct 25, 2011 |
| Priority date | — |
| Expiry date | Aug 28, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0821
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective neuroprotective agents. Due to their strong central nervous system (CNS) activity, the compounds can be used to enhance memory and to treat a variety of neurological disorders. The compounds are particularly useful for treating neurological disorders caused by, or associated with, CNS trauma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.