Anti-proliferative combination therapy using certain platinum-based chemotherapeutic agents and EGFR inhibitors or pyrimidine analogues

US8048888B2 · kind B2 · utility

Assignee

• Agennix AG · US

Inventors

• Katja Wosikowski-Buters · Poing, DE
• Christoph Schaab · Martinsried, DE
• Marino Schuhmacher · Birkenfeld, DE
• Franz Obermayr · Fürstenfeldbruck, DE
• Igor Ivanov · Markt Indersdorf, DE

Key dates

• Filing date: Nov 13, 2006
• Grant date: Nov 1, 2011
• Expiry date: Dec 13, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention describes a method or uses of prevention and/or treatment of a cancer or a tumor, and in particular to a combination therapy, methods, compositions and pharmaceutical packages comprising an inhibitor of receptors of the EGFR family or a chemotherapeutically active pyrimidine analogue and certain platinum-based chemotherapeutic agents.