Optically pure and enriched isomers of chelating ligands and contrast agents

US8048906B2 · kind B2 · utility

Assignee

• Catalyst Medical · US

Inventors

• John Amedio · Franklin, US
• Peter Caravan · Cambridge, US
• Vincent Jacques · Somerville, US
• Kevin Zhou · Mansfield, US
• Stuart B. Levy · Boston, US
• Shirley Kalogeropoulos · Lowell, US
• Matthew Greenfield · Middleton, US

Key dates

• Filing date: Oct 4, 2006
• Grant date: Nov 1, 2011
• Expiry date: Mar 3, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D257/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Organic chelating ligands, organic chelating ligand precursors, and metal chelates are disclosed. Methods for synthesizing the same are also described, including methods for preparing optically-enriched or optically-pure compositions of the same.