Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8049061B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 25, 2008 |
| Grant date | Nov 1, 2011 |
| Priority date | — |
| Expiry date | Sep 25, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/1088
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent incorporated therein. The hydrogel polymer can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a second coating including a protective substance surrounding the hydrogel polymer having a therapeutic agent therein. The matrix of fiber elements can be formed by electrospinning. A process of delivering a therapeutic agent to a target site includes providing an intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member including a hydrogel polymer having a therapeutic agent dispersed therein, and advancing the catheter device at a desired treatment site. Once at the desired treatment site, fluid is introduced into the inflation lumen to expand the expandable member from a first profile to a second profile, and the therapeutic agent is released from the hydrogel polymer and delivered to the desired treatment site.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.