Crystallization of chemical species/polymorphs and microfluidic apparatus and screening methodology therefor
US8053242B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Sep 3, 2009 |
| Grant date | Nov 8, 2011 |
| Priority date | — |
| Expiry date | Sep 3, 2029 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/1822
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The crystallization of chemical species/polymorphs comprises forming droplets of a solution of a substance with optionally different concentrations of said substance in an inert phase; producing and storing the droplets in at least one storage microchannel (1); forming crystals in all droplets; increasing the temperature in order to induce the dissolution of at least a portion of the crystals in at least some droplets; and analyzing the crystallization and dissolution process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.