Composition and method of treating hearing loss
US8053424B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 19, 2010 |
| Grant date | Nov 8, 2011 |
| Priority date | — |
| Expiry date | Jul 19, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P27/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition for treating hearing loss includes components that function through different biological mechanisms to provide an additive effect that is greater than the effect of the individual components alone. The composition includes a biologically effective amount of vitamin E for inhibiting propagation of lipid peroxidation that contributes to hearing loss. The composition also includes a biologically effective amount of a salicylate for reducing hydroxyl radicals that contribute to hearing loss. A method of treating hearing loss includes the step of internally administering the composition, as described above, to a mammal within three days of trauma to a middle or inner ear of the mammal. In other words, the composition is effective even when administered as late as three days after trauma to a middle or inner ear of a mammal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.