Devices and methods for extracorporeal ablation of circulating cells
US8057418B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 29, 2008 |
| Grant date | Nov 15, 2011 |
| Priority date | — |
| Expiry date | Mar 9, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M1/369
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and devices are provided for the extracorporeal ablation of target cells circulating in blood of an organism. Exogenous material introduced into the blood preferentially associates with target cells (e.g. cancer cells, bacteria, viruses) in the blood. An extracorporeal continuous flow pathway accesses the patient's blood to apply an external energy source to the blood at an ex vivo ablation device in a portion of the extracorporeal continuous flow pathway. The exogenous material interact with the applied energy so as to result in the damage or death of the target cells. The blood is then returned to the body in a continuous-flow pattern. By applying the energy while the blood is in the ex vivo ablation device, shielding of the target cells by the body is reduced and detrimental effects on the organs and tissues of the body are avoided or mitigated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.