Patent · US Active

Modification of protein glycosylation in methylotrophic yeast

US8058053B2 · kind B2 · utility

14Cited by

5References

29Claims

0Family size

Assignees

VIB VZW · BE
UNIVERSITEIT GENT · BE
Research Corporation Technologies, Inc. · US

Inventors

Roland Contreras · Merelbeke, BE
Nico Callewaert · Nevele, BE
Wouter Vervecken · Landskouter, BE
Vladimir Kaigorodov · Evergem, BE

Key dates

Filing date	Feb 11, 2009
Grant date	Nov 15, 2011
Priority date	—
Expiry date	Feb 11, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P21/005
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable of producing glycoproteins with mammalian-like glycosylation. Glycoproteins produced from the genetically engineered methylotrophic yeast strains are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.