Patent · US Active

Method of producing region-specific neurons from human neuronal stem cells

US8058063B2 · kind B2 · utility

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4References

41Claims

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Assignee

The Board of Regents of the University of Texas System · US

Inventor

Ping-Ching Wu · Tainan, TW

Key dates

Filing date	Jun 19, 2002
Grant date	Nov 15, 2011
Priority date	—
Expiry date	Sep 28, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2503/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method of priming neural stem cells in vitro by adhesively culturing in a mixture of basic fibroblast growth factor, laminin and heparin to differentiate into specific neuronal phenotypes, including cholinergic, glutamatergic and GABAergic neurons, in a region-specific manner, when transplanted in vivo.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.