Patent · US Active

Polyphenol proteasome inhibitors, synthesis, and methods of use

US8058310B2 · kind B2 · utility

1Cited by
2References
14Claims
0Family size

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Key dates

Filing dateFeb 25, 2010
Grant dateNov 15, 2011
Priority date
Expiry dateFeb 25, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.