Patent · US Active

Imaging 18F or 11C-labelled alkylthiophenyl guanidines

US8058311B2 · kind B2 · utility

3Cited by

0References

5Claims

0Family size

Assignee

Hammersmith Imanet Limited · GB

Inventors

Edward George Robins · London, GB
Erik Arstad · London, GB

Key dates

Filing date	Jun 23, 2006
Grant date	Nov 15, 2011
Priority date	—
Expiry date	Nov 30, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B59/001
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention provides a compound of formula (I); or a salt or solvate thereof, wherein: R1 is hydrogen or C1-4 alkyl; R2 and R4 are each independently selected from C1-4 alkyl, [11C]C1-4 alkyl, and [18F]—C1-4 fluoroalkyl provided that at least one of R2 and R4 is [11C]C1-4 alkyl or [18F]—C1-4 fluoroalkyl; and R3 is halo. Such compounds having use for imaging central nervous system receptors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.