Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
US8058314B2 · kind B2 · utility
1Cited by
37References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 2007 |
| Grant date | Nov 15, 2011 |
| Priority date | — |
| Expiry date | Jul 13, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91102
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.