Method of serum pre-treatment for glycomic analysis
US8058409B2 · kind B2 · utility
3Cited by
1References
5Claims
0Family size
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Key dates
| Filing date | Jun 29, 2007 |
| Grant date | Nov 15, 2011 |
| Priority date | — |
| Expiry date | Oct 5, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/66
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A means for pre-treatment in glycomic analysis of a glycoprotein is provided by the present invention.A salt of the general formula (I):wherein Z, X, R1, R2, M, m and n are the same as described in DESCRIPTION,is useful as a protein solubilizer, and an oligosaccharide is efficiently released from a sample if reductive alkylation and/or digestion by a proteinase are carried out under the presence of the said solubilizer at the first step in the glycomic analysis of glycoprotein derived from a living body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.