Patent · US Active

Fluorescent double stranded DNA binding dyes

US8058431B2 · kind B2 · utility

3Cited by

2References

3Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Hans-Peter Josel · Weilheim, DE
Dieter Heindl · Munich, DE
Bernhard Irlinger · Munich, DE
Christian Weilke · Penzberg, DE

Key dates

Filing date	Apr 3, 2009
Grant date	Nov 15, 2011
Priority date	—
Expiry date	Sep 15, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC09B23/04
WIPO fieldBasic materials chemistry
WIPO sectorChemistry

Abstract

Disclosed is a fluorescent dye comprising a benzothiazolium moiety and a pyrimidinium moiety connected by a mono-methine bridge, characterized in that (i) the 2-position of the pyrimidine carries a substituent which starts with a C-atom and (ii) the 5- and 6- positions of the pyrimidine ring are an integral part of a further aromatic ring structure as exemplified by the following:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.