Immunogens for meningitidis-A vaccines
US8062641B2 · kind B2 · utility
6Cited by
2References
43Claims
0Family size
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Key dates
| Filing date | May 8, 2006 |
| Grant date | Nov 22, 2011 |
| Priority date | — |
| Expiry date | May 18, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H13/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An oligosaccharide useful for a Meningitidis A vaccine contains a first mannose unit having a spacer in the alpha configuration at C-1, which spacer is capable of conjugating to a protein, and which is connected to a second mannose unit through a 1,6-linkage which connects C-6 of the first unit to C-1 of the second unit, wherein the 1,6-linkage comprises a phosphonate. Related methods of making such compounds, analogous compounds, or intermediates thereof are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.