Apparatus for isolating a nucleic acid from a sample

US8062846B2 · kind B2 · utility

Assignees

• Massachusetts Institute of Technology · US
• Smiths Detection-Edgewood, Inc. · US

Inventors

• Laura Bortolin · Newton, US
• Lalitha Parameswaran · Burlington, US
• James D. Harper · Hazel Green, US
• Johanna Bobrow · Somerville, US
• Mark A. Hollis · Concord, US
• Drew Chapman Brown · Towson, US
• Eric Scott Clasen · Fryeburg, US
• John Calvin Schmidt · Baltimore, US

Key dates

• Filing date: May 18, 2007
• Grant date: Nov 22, 2011
• Expiry date: May 18, 2027

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0683
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

An apparatus for preparing a nucleic acid component of a sample for amplification includes a porous support having an agent that deactivates a nucleic acid amplification inhibitor component of the sample. The apparatus further includes a housing with an opening and defining an interior. The interior of the housing is in fluid communication with the porous support, and at least a portion of a fluid directed through the opening is directed through at least a portion of the porous support. The apparatus also includes a magnetic substrate for separating nucleic acid from a sample.