Monoclonal antibody specifically recognizing modification site after translation of p53 and kit for assaying modification site containing the same
US8062887B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 31, 2006 |
| Grant date | Nov 22, 2011 |
| Priority date | — |
| Expiry date | Oct 17, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4748
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a monoclonal antibody recognizing modification after translation of p53 in a manner specific to a modification site, an antibody microarray comprising the antibody immobilized on a substrate, etc. Disclosed is a monoclonal antibody which reacts specifically with a peptide consisting of an amino acid sequence of at least 6 consecutive amino acids containing a predetermined amino acid residue of the amino acid sequence represented by SEQ ID NO: 1, wherein the amino acid residue is phosphorylated or acetylated, or with a peptide having one to several arbitrary amino acids added to the above peptide, but does not react with the above peptide which is not phosphorylated or acetylated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.