High throughput assays for transmissible spongiform encephalopathies (TSE)
US8062888B2 · kind B2 · utility
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Key dates
| Filing date | Apr 25, 2005 |
| Grant date | Nov 22, 2011 |
| Priority date | — |
| Expiry date | Mar 21, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2828
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Stable cell lines which produce the pathological form of PrP after infection with the infectious agent for CJD provide a high throughput assay to identify suitable treatment protocols and compositions. The stable cell lines also provide rich source of infectious CJD agent. They also may be used to identify vaccine candidates. Co-culture of neuronal cells with cells to be tested for infection with a TSE agent also provides a high throughput method for identifying infected cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.