Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
US8063050B2 · kind B2 · utility
36Cited by
24References
103Claims
0Family size
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Key dates
| Filing date | Jul 5, 2007 |
| Grant date | Nov 22, 2011 |
| Priority date | — |
| Expiry date | Jul 19, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I:Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.