Patent · US Active

Formulations for parenteral administration of (e)-2, 6-dialkoxystyryl 4-substituted benzylsulfones

US8063109B2 · kind B2 · utility

4Cited by

6References

20Claims

0Family size

Assignee

ONCONOVA THERAPEUTICS, INC. · US

Inventors

Stanley C. Bell · Narberth, US
Albert Wong · Philadelphia, US
Manoj Maniar · Baltimore, US

Key dates

Filing date	Jul 15, 2005
Grant date	Nov 22, 2011
Priority date	—
Expiry date	Aug 5, 2027

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Formulations are provided for parenteral administration of (amino substituted (e)-2,6-dialkoxystyryl 4-substituted benzylsulfones and the sodium and potassium salts thereof for the prevention and/or treatment of conditions mediated by abnormal cell proliferation. Composition for parenteral administration are provided which comprise an effective amount of compound of formula Ior a compound of formula IIaand at least about 50% by weight of at least one water soluble polymer selected from the group consisting essentially of polyethylene glycol (PEG), poly-oxyethylene, poly-oxyethylene-poly-oxypropylene copolymers, polyglycerol, polyvinylalcohol, polyvinylpyrrolidone (PVP), polyvinylpyridine N-oxide, copolymer of vinylpyridine N-oxide and vinylpyridine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.