Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
US8063227B2 · kind B2 · utility
18Cited by
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Key dates
| Filing date | Jul 14, 2009 |
| Grant date | Nov 22, 2011 |
| Priority date | — |
| Expiry date | Jul 14, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.