Substituted 7-sulfanylmethyl-, 7-sulfinylmethyl- and 7-sulfonylmethylindoles and the use thereof

US8063234B2 · kind B2 · utility

Assignee

• Bayer Schering Pharma AG · DE

Inventors

• Peter Kolkhof · Wuppertal, DE
• Astrid Brüns · Wuppertal, DE
• Kai Thede · Leverkusen, DE
• Karl-Heinz Schlemmer · Wuppertal, DE
• Alexander Hillisch · Solingen, DE
• Dieter Lang · Velbert, DE
• Michael Gerisch · Wuppertal, DE
• Andreas Goeller · Wuppertal, DE
• Rolf Grosser · Schwandorf, DE
• Carsten Schmeck · Wuppertal, DE
• Elisabeth Woltering · Hilden, DE
• Olaf Prien · Berlin, DE
• Holger Paulsen · Wuppertal, DE
• Armin Kern · Wuppertal, DE

Key dates

• Filing date: Jun 24, 2009
• Grant date: Nov 22, 2011
• Expiry date: Aug 28, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel 7-sulfanylmethyl-, 7-sulfinylmethyl- and 7-sulfonylmethylindole derivatives, processes for the preparation thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases, and the use thereof for the manufacture of medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.