Method for generating replication defective viral vectors that are helper free
US8067156B2 · kind B2 · utility
8Cited by
8References
37Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 31, 2002 |
| Grant date | Nov 29, 2011 |
| Priority date | — |
| Expiry date | Jan 30, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14162
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Sequences are provided that are capable of directing circular adeno-associated virus replication, useful in vectors for providing therapeutic agents to a subject in need thereof. The vectors of the invention are particularly useful in the treatment of acute medical conditions requiring rapid gene expression. Further provided are methods for producing packaged defective viral vectors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.