Linoleic acid preparations for the topical treatment of male and female pattern androgenetic alopecia, age-related alopecia, and keratosis pilaris
US8067470B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Feb 1, 2008 |
| Grant date | Nov 29, 2011 |
| Priority date | — |
| Expiry date | May 9, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q7/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A preparation for the topical application of linoleic acid to treat male and female androgenetic alopecia, age-related alopecia, and keratosis pilaris contains between about 0.1% and about 10%, preferably between about 1% and about 5%, and specifically about 2% linoleic acid by volume in its carrier vehicle. This acts to correct the local linoleic acid deficiency that exists in the follicles in these conditions and provides linoleic acid to suppress growth of Propionibacterium acnes with resultant reduction in its porphyrin production which in turn reduces microinflammation and altered keratinization that damages follicles and eliminates functioning follicles in alopecia and causes follicle plugging in keratosis pilaris.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.