Methods of using human tissue factor-producing knock-in mice
US8067665B2 · kind B2 · utility
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Key dates
| Filing date | Aug 12, 2009 |
| Grant date | Nov 29, 2011 |
| Priority date | — |
| Expiry date | Aug 26, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-human animal that produces human tissue factor (TF) without substantially producing non-human animal tissue factor, said animal having a genome in which cDNA encoding human TF has been inserted upstream of the translation initiation codon for the non-human animal genomic TF gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.