Biosensing apparatus and system
US8068995B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2009 |
| Grant date | Nov 29, 2011 |
| Priority date | — |
| Expiry date | Feb 25, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/932
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A bio-sensing system comprises a light source, a bio-sensing apparatus, a detecting platform, and a processing unit. A bio-sensing apparatus further comprising a substrate, a sample with at least one analyte, at least one grating bound on the substrate for diffracting a light beam in a reflection mode and outputting at least one output light beam, a plurality of nanoparticles being bound on one side of the grating, a molecular recognition unit bound on said nanoparticle surface, and a cover plate covering the nanoparticle-modified side of the substrate. The detecting platform receives a signal while the at least one output light beam passing through the bio-sensing apparatus. The processing unit couples with the detecting platform for receiving and analyzing the signal. Wherein when the analyte passes through the microfludic channel to contact with said nanoparticles, the at least one output light beam changes in accordance with the refractive index of the sample or in accordance with the interaction of the analyte with said molecular recognition unit bound on said nanoparticle surface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.