Patent · US Active

Pestivirus mutant for use in a vaccine

US8071108B2 · kind B2 · utility

0Cited by

1References

9Claims

0Family size

Assignee

INTERVET INTERNATIONAL B.V · NL

Inventors

Martin Beer · Greifswald, DE
Ilona Reimann · Greifswald, DE
Patricia Koenig · Greifswald, DE

Key dates

Filing date	Sep 20, 2007
Grant date	Dec 6, 2011
Priority date	—
Expiry date	Nov 12, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2770/24362
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention comprises new pestivirus mutants, characterized in that the mutants are based on a cp strain of the virus wherein part of the gene sequence encoding the Npro region is deleted, except that the deleted part does not encompass the coding sequence for the N-terminal twelve amino acids of the Npro protein. Preferably the pestivirus is the Bovine Viral Diarrhea Virus (BVDV). It was found that a mutant according to the invention is a safe and efficient vaccine candidate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.