Guanidinium derivatives for improved cellular transport
US8071535B2 · kind B2 · utility
4Cited by
5References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 10, 2004 |
| Grant date | Dec 6, 2011 |
| Priority date | — |
| Expiry date | May 13, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Reagents and methods useful for the synthesis of conjugates comprising guanidinylated cyclic acetals are provided. Also provided are methods for increasing the cellular uptake of various therapeutic compounds and treatment modalities using these conjugates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.