Methods for preparing internally constrained peptides and peptidomimetics
US8071541B2 · kind B2 · utility
49Cited by
6References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2010 |
| Grant date | Dec 6, 2011 |
| Priority date | — |
| Expiry date | Feb 24, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for preparing a peptide having a stable, internally constrained alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region and a method of stabilizing an alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region within a peptide structure. The resulting peptides and methods of using them are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.