Purine derivatives as a2a agonists

US8071565B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Robin Alec Fairhurst · Riehen, CH
• Roger John Taylor · Southwater, GB

Key dates

• Filing date: Jul 11, 2007
• Grant date: Dec 6, 2011
• Expiry date: Mar 18, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein W, R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.