Patent · US Active

6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors

US8071612B2 · kind B2 · utility

0Cited by

1References

5Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Dominique Jean-Pierre Mabire · La Saussaye, FR
Jérôme Emile Georges Guillemont · Andé, FR
Jacobus Alphonsus Josephus Van Dun · Kasterlee, BE
Maria Victorina Francisca Somers · Vosselaar, BE
Walter Boudewijn Leopold Wouters · Kapellen, BE

Key dates

Filing date	Nov 19, 2010
Grant date	Dec 6, 2011
Priority date	—
Expiry date	Nov 19, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (I) and compounds of formula (VII-a) as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitorswherein n, R1, R2, R3, R4, R5, R6, R7, Re, Rd and X have defined meanings.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.