Patent · US Active

Nucleic acid-based detection

US8071734B2 · kind B2 · utility

9Cited by

17References

39Claims

0Family size

Assignee

BRANDEIS UNIVERSITY · US

Inventors

Martin Stanton · Stow, US
Pieter Wensink · Wellesley, US
Alexander Stewart · Menifee, US

Key dates

Filing date	Dec 22, 2006
Grant date	Dec 6, 2011
Priority date	—
Expiry date	Oct 22, 2029

Classification

Technology area (CPC G)Physics
CPC primaryG01N21/6458
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to compositions, systems, and methods for simultaneously detecting the presence and quantity of one or more different compounds in a sample using aptamer beacons. Aptamer beacons are oligonucleotides that have a binding region that can bind to a non-nucleotide target molecule, such as a protein, a steroid, or an inorganic molecule. New aptamer beacons having binding regions configured to bind to different target molecules can be used in solution-based and solid, array-based systems. The aptamer beacons can be attached to solid supports, e.g., at different predetermined points in two-dimensional arrays. The invention includes devices, methods, and computer software for carrying out the methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.