Patent · US Active

CTIP2 expression in squamous cell carcinoma

US8071815B2 · kind B2 · utility

2Cited by

2References

8Claims

0Family size

Inventors

Arup K. Indra · Corvallis, US
Gitali Indra · Corvallis, US
Joseph Abecassis · Strasbourg, FR
Mark Leid · Strasbourg, FR

Key dates

Filing date	Jul 17, 2009
Grant date	Dec 6, 2011
Priority date	—
Expiry date	Nov 20, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present disclosure provides methods of diagnosing and staging squamous cell carcinomas, for instance head and neck (HNSCC), by detecting chicken ovalbumin upstream promoter-transcription factor-interacting protein 2 (CTIP2) expression. For example, it is demonstrated herein that expression of CTIP2 is increased in SCC relative to a corresponding normal sample. Also included are kits for detecting SCC, as well as methods for identifying CTIP2 inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.