Systems and methods for replacing signal artifacts in a glucose sensor data stream

US8073520B2 · kind B2 · utility

Assignee

• Dexcom, Inc. · US

Inventors

• Apurv Ullas Kamath · San Diego, US
• Paul V. Goode · Round Rock, US
• James H. Brauker · Cement City, US
• James Patrick Thrower · Oakland, US
• Victoria Carr-Brendel · San Diego, US

Key dates

• Filing date: May 25, 2010
• Grant date: Dec 6, 2011
• Expiry date: May 25, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B2562/08
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.