Method to increase the yield and improve purification of products from transaminase reactions
US8076106B2 · kind B2 · utility
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8References
14Claims
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Key dates
| Filing date | Aug 6, 2009 |
| Grant date | Dec 13, 2011 |
| Priority date | — |
| Expiry date | Jun 9, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/22
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to produce a keto acid by-product and an amino acid or amine product. Further reacting the keto acid by-product with a peroxide to increase the yield of additional amino acid or amine product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.