Patent · US Active

Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

US8076108B2 · kind B2 · utility

11Cited by

21References

8Claims

0Family size

Assignee

CARGILL, INCORPORATED · US

Inventors

Brian Brazeau · Oskaloosa, US
Mervyn de Souza · Windom, US
Steven John Gort · Brooklyn Center, US
Paula M. Hicks · Eden Prairie, US
Sherry Kollmann · Maple Grove, US
Jose Laplaza · Sun Prairie, US
Sara C. McFarlan · Windom, US
Fernando A. Sanchez-Riera · South San Francisco, US
Christopher Solheid · Minneapolis, US

Key dates

Filing date	Mar 6, 2007
Grant date	Dec 13, 2011
Priority date	—
Expiry date	Mar 13, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P17/10
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.