Method for obtaining antigen-specific Tr1 regulatory lymphocytes
US8076133B2 · kind B2 · utility
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2References
8Claims
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Assignee
Inventors
Key dates
| Filing date | May 10, 2002 |
| Grant date | Dec 13, 2011 |
| Priority date | — |
| Expiry date | Mar 29, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/99
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a method for preparing antigen-specific Tr1 regulatory lymphocytes. The inventive method involves the use of artificial antigen-presenting cells expressing a molecule from the HLA class II system and a human LFA-3 molecule and expressing none of the B7-1, B7-2, B7-H1, CD40, CD23, or ICAM-1 costimulatory molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.