Administration of carboline derivatives useful in the treatment of cancer and other diseases
US8076352B2 · kind B2 · utility
23Cited by
34References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 13, 2007 |
| Grant date | Dec 13, 2011 |
| Priority date | — |
| Expiry date | Jun 25, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and compositions, and methods for the administration and use of those compounds. provided. In one aspect of the invention, compounds useful in the inhibition of VEGF production, in the treatment of solid tumor cancer, and in reducing serum, plasma, and/or tumor VEGF levels, are provided. In another aspect of the invention, methods are provided for the inhibition of VEGF production, the treatment of cancer, and the reduction of plasma and/or tumor VEGF levels, using the compounds of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.