Methods and compositions for determining the purity of and purifying chemically synthesized nucleic acids
US8076461B2 · kind B2 · utility
3Cited by
33References
11Claims
0Family size
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Key dates
| Filing date | Dec 24, 2003 |
| Grant date | Dec 13, 2011 |
| Priority date | — |
| Expiry date | Mar 2, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An antibody microarray is described comprising a plurality of antibodies immobilized on a substrate, wherein each antibody specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having an organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are disclosed, along with cells for making such antibodies. Methods of making and using such antibody microarrays are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.