Transgenic mouse defective in WW45 function and use in screening compounds for anti-tunour activity
US8076532B2 · kind B2 · utility
3Cited by
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5Claims
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Key dates
| Filing date | Mar 27, 2009 |
| Grant date | Dec 13, 2011 |
| Priority date | — |
| Expiry date | Oct 10, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/405
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Mechanisms regulating cell proliferation stop and differentiation initiation during the development stage of mammalian embryo, and the proteins involved therein, are presented. Differentiation regulators, methods of regulating differentiation, transgenic organisms with loss of expression of the differentiation regulator, and methods of preparing the transgenic organisms, are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.