Patent · US Active

Method for determining predisposition to pulmonary infection

US8080394B2 · kind B2 · utility

23Cited by

0References

14Claims

0Family size

Assignees

The Brigham and Women's Hospital, Inc. · US
Children's Medical Center Corporation · US
President and Fellows of Harvard College · US

Inventors

Hara Levy · Bayside, US
Craig Gerard · Dover, US
Gerald B. Pier · Brookline, US
Scott Weiss · Sharon, US
Christoph Lange · Berlin, DE

Key dates

Filing date	Apr 28, 2008
Grant date	Dec 20, 2011
Priority date	—
Expiry date	Jun 22, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are methods and materials for diagnosing a subject's predisposition for pulmonary infection in a CF subject by detecting a pulmonary infection genetic marker. Pulmonary infection markers have been identified in the IL-1 gene cluster and may be useful in predicting CF disease progression and assessing a CF subject's response to therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.